Publications
At Stanford
10) Isaac A. Paddy, Laura M. K. Dassama. Identifying opportunity targets in gram-negative pathogens for infectious disease mitigation. ACS Cent. Sci. 2024, accepted.
9) Jonathan Chiu-Chun Chou, Laura M. K. Dassama. Lipid trafficking in diverse bacteria. Acc. Chem. Res. 2024, in press. https://pubs.acs.org/doi/10.1021/acs.accounts.4c00540
8) Poulami Chatterjee, Laura M. K. Dassama. Unveiling of a messenger: Gut microbes make a neuroactive signal . Cell 2024, 187, 2903-2904
7) Jonathan Chiu-Chun Chou, Cassandra M. Decosto*, Poulami Chatterjee*, Laura M. K. Dassama. Rapid proteome-wide prediction of lipid-interacting proteins through ligand-guided structural genomics. biorxiv 2024, doi: https://doi.org/10.1101/2024.01.26.577452
6) Liting Zhai, Amber C. Bonds, Clyde Smith, Hannah Oo, Jonathan Chiu-Chun Chou, Paula V. Welander, Laura M. K. Dassama. Novel sterol binding domains in bacteria. eLife. 2024, Feb 8;12:RP90696. doi: 10.7554/eLife.90696
5) Fangfang Shen, Laura M. K. Dassama. Opportunities and challenges of protein-based targeted protein degradation. Chemical Science 2023, 14, 8433-8447
4) Liting Zhai*, Jonathan Chiu-Chun Chou*, Hannah Oo, Laura M. K. Dassama. Structures and mechanisms of a novel bacterial transport system for fatty acids. ChemBioChem 2023, 24, e202300156 (ChemBioTalents Issue)
3) Maolu Yin, Manizheh Izadi, Karin Tenglin, Thibault Viennet, Liting Zhai, Ge Zheng, Haribabu Arthanari, Laura M. K. Dassama, Stuart H. Orkin. Evolution of nanobodies specific for BCL11A. Proc. Natl. Acad. Sci. USA 2023, 120, e2218959120
2) Fangfang Shen, Ge Zheng, Mekedlawit Setegne, Karin Tenglin, Manizheh Izadi, Henry Xie, Liting Zhai, Stuart H. Orkin, Laura M. K. Dassama. A cell-permeant nanobody-based degrader that induces fetal hemoglobin. ACS Cent Sci. 2022, 8, 1695-1703
1) Jonathan Chiu-Chun Chou, Veronica E. Stafford, Grace E. Kenney, Laura M. K. Dassama. The enzymology of oxazolone and thioamide synthesis in methanobactin. Methods Enzymol. 2021, 656, 341-373
*= equal contribution
Before Stanford
15) Martin Srnec*, Shyam R. Iyer*, Laura M. K. Dassama, Kiyoung Park, Shaun D. Wong, Kyle D. Sutherlin, Yoshitaka Yoda, Yasuhiro Kobayashi, Masayuki Kurokuzu, Makina Saito, Makoto Seto, Carsten Krebs, J. Martin Bollinger Jr, Edward I. Solomon. Nuclear resonance vibrational spectroscopic definition of the facial triad Fe IV═O intermediate in taurine dioxygenase: evaluation of structural contributions to hydrogen atom abstraction. J. Am. Chem. Soc. 2020, 42, 18886-18896
14) Grace E. Kenney*, Laura M. K. Dassama*, Anastasia C. Manesis, Matthew O. Ross, Siyu Chen, Brian M. Hoffman, and Amy C. Rosenzweig. MbnH is a diheme MauG-like protein associated with microbial copper homeostasis. J. Biol. Chem. 2019, 294, 16141-16151.
13) Falak Sher*, Mir Hossain*, Davide Seruggia*, Vivien Schoonenberg, Qiuming Yao, Paolo Cifani, Laura M. K. Dassama, Mitchel Cole, Claudio Macias-Trevino, Kevin Luk, Connor McGuckin, Patrick Schupp, Matthew Canver, Ryo Kurita, Yukio Nakamura, Yuko Fujiwara, Scot Wolfe, Luca Pinello, Takahiro Maeda, Alex Kentsis, Stuart Orkin, Daniel Bauer. Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. Nature Genetics 2019, 51, 1149-1159.
12) Grace E. Kenney, Laura M. K. Dassama, Maria-Eirini Pandelia, Anthony S. Gizzi, Ryan J. Martinie, Peng Gao, Caroline J. DeHart, Luis F. Schachner, Owen S. Skinner, Soo Y. Ro, Xiao Zhu, Monica Sadek, Paul M. Thomas, Steven C. Almo, J. Martin Bollinger Jr., Carsten Krebs, Neil L. Kelleher, Amy C. Rosenzweig. The Biosynthesis of Methanobactin. Science 2018, 359, 1411-1416.
11) Spencer C. Peck, Chen Wang, Laura M. K. Dassama, Bo Zhang, Yisong Guo, Lauren J. Rajakovich, J. Martin Bollinger, Jr., Carsten Krebs, and Wilfred A. van der Donk. O-H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase. J. Am. Chem. Soc. 2017, 139, 20145-2052.
10) Laura M. K. Dassama*, Grace E. Kenney*, and Amy C. Rosenzweig. Methanobactins: From Genome to Function. Metallomics 2017, 9, 7-20.
9) Laura M. K. Dassama, Grace E. Kenney, Soo Y. Ro, Eliza L. Zielanzinski, and Amy C. Rosenzweig. The Methanobactin Transport Machinery. Proc. Natl. Acad. Sci. USA 2016, 113, 13027-13032.
8) Jovan Livada*, Ryan J. Martinie*, Laura M. K. Dassama, Carsten Krebs, J. Martin Bollinger, Jr., Alexey Silakov. Direct Measurement of the Radical Translocation Distance in the Class I Ribonucleotide Reductase from Chlamydia trachomatis. J. Phys. Chem. B. 2015, 119, 13777-13784.
7) Yeonju Kwak, Wei Jiang, Laura M. K. Dassama, Kiyoung Park, Caleb B. Bell, Lei V. Liu, Shaun D. Wong, Makina Saito, Yasuhiro Kobayashi, Shinji Kitao, Makoto Seto, Yoshitaka Yoda, Esen E. Alp, Jiyong Zhao, J. Martin Bollinger, Jr., Carsten Krebs, and Edward I. Solomon. Geometric and Electronic Structure of the Mn(IV)/Fe(III) Cofactor in Class Ic Ribonucleotide Reductase: Correlation to the Class Ia Binuclear Non-Heme Iron Enzyme. J. Am. Chem. Soc. 2013, 135, 17573-17584.
6) Laura M. K. Dassama, Alexey Silakov, Courtney M. Krest, Julio C. Calixto, Carsten Krebs, J. Martin Bollinger, Jr., and Michael T. Green. A 2.8 Å Fe−Fe Separation in the Fe2III/IV Intermediate (X) from Escherichia coli Ribonucleotide Reductase. J. Am. Chem. Soc. 2013, 135, 16758-16761.
5) Laura M. K. Dassama, Carsten Krebs, Amy C. Rosenzweig, J. Martin Bollinger, Jr., and Amie K. Boal. Structural Basis for Assembly of the MnIV/FeIII Cofactor in the Class Ic Ribonucleotide Reductase from Chlamydia trachomatis. Biochemistry 2013, 52, 6424-6436.
4) Carsten Krebs, Laura M. K. Dassama, Megan L. Matthews, Wei Jiang, John C. Price, Victoria Korboukh, Ning Li, and J. Martin Bollinger, Jr. Novel Approaches for the Accumulation of Oxygenated Intermediates to Multi-Millimolar Concentrations. Coord. Chem. Rev. 2013, 257, 234-253.
3) Laura M. K. Dassama*, Wei Jiang*, Paul T. Varano, Maria-Eirini Pandelia, Denise A. Conner, Jiajia Xie, J. Martin Bollinger, Jr., and Carsten Krebs. Radical-Translocation Intermediates and Hurdling of Pathway Defects in “Super-oxidized” (MnIV/FeIV) Chlamydia trachomatis Ribonucleotide Reductase. J. Am. Chem. Soc. 2012, 134, 20498-20506.
2) Laura M. K. Dassama, Timothy H. Yosca, Denise A. Conner, Michael H. Lee, Béatrice Blanc, Bennett R. Streit, Michael T. Green, Jennifer L. DuBois, Carsten Krebs, and J. Martin Bollinger, Jr. O2-Evolving Chlorite Dismutase as a Tool for Studying O2-Utilizing Enzymes. Biochemistry 2012, 51, 1607-1616.
1) Laura M. K. Dassama*, Amie K. Boal*, Carsten Krebs, Amy C. Rosenzweig, and J. Martin Bollinger, Jr. Evidence That the β Subunit of Chlamydia trachomatis Ribonucleotide Reductase Is Active with the Manganese Ion of Its Manganese(IV)/Iron(III) Cofactor in Site 1. J. Am. Chem. Soc. 2012, 134, 2520-2523.
*= equal contribution